Xian Yan-Fang
The Chinese University of Hong Kong, Hong Kong
Biography
Xian Yan-Fang, a Postdoctoral Fellow at School of Chinese Medicine, The Chinese University of Hong Kong, obtained her PhD degree in 2013 from The Chinese University of Hong Kong. She has rich experience in studying the Chinese medicines and neuroscience. Her team has investigated the neuroprotective effects of Chinese medicines and natural products for more than 10 years. She has published 14 original research articles based on her experimental findings in various SCI-listed academic journals as the first author. In this study, she aimed to examine the anti-depressant-like effect of isorhynchophylline (IRN) in Chronic Unpredictable Mild Stress (CUMS)-treated rats and explore the molecular mechanisms in the hippocampus and frontal cortex of rats. The results showed that IRN treatment could reverse the behavioral and biochemical changes induced by CUMS. The results from the present proposed study would form foundation that may lead to future clinical trial of IRN on depression.