Lin Zhi-Xiu
The Chinese University of Hong Kong, Hong Kong
Biography
Lin Zhi-Xiu is the Acting Director and Associate Professor of School of Chinese Medicine, The Chinese University of Hong Kong. He obtained his PhD degree in Pharmacognosy from King’s College London in 1999. He has rich experience in studying the neuroprotective effects of Chinese medicines and natural products. Over the years, he has published over 150 research articles on Chinese medicines and natural products, among them, over 110 articles are in the SCI-cited journals. This study aimed to investigate the neuroprotective effect of isorhycnhophylline (IRN) in aluminum chloride (AlCl3)-treated mice and explore the molecular mechanisms in the brain of mice. The results showed that IRN treatment could improve the cognitive deficits and reverse the biochemical changes induced by AlCl3. The results from the present proposed study would form a solid stepping stone leading to future clinical trial of IRN on Alzheimer’s disease.
Abstract
Abstract : Isorhynchophylline improves learning and memory impairments induced by aluminum chloride in mice